Health Center

1. Metformin-associated lactic acidosis in intensive care unit.
ABSTRACT: INTRODUCTION: Metformin-associated lactic acidosis (MALA) is a classical side effect of metformin and is known to be a severe disease with a high mortality rate. MALA's treatment by dialysis is controversial and is subject to ...

2. DailyMed: About DailyMed
In a patient with lactic acidosis who is taking RIOMET, the drug should be discontinued immediately and general supportive measures promptly instituted. Because metformin hydrochloride is dialyzable (with a clearance of up to 170 mL/min ...

3. Metformin, Sulfonylureas, or Other Antidiabetes Drugs and the Risk ...
OBJECTIVE—Lactic acidosis has been associated with use of metformin. Hypoglycemia is a major concern using sulfonylureas. The aim of this study was to compare the risk of lactic acidosis and hypoglycemia among patients with type 2 ...

4. Metformin: consensus statement published on Diabetes Care ...
The UKPDS demonstrated a beneficial effect of metformin therapy on CVD outcomes (7), which needs to be confirmed. Renal dysfunction is considered a contraindication to metformin use because it may increase the risk of lactic acidosis, ...

5. Metformin
WARNING: Metformin may rarely cause a condition called lactic acidosis, which is sometimes fatal. Seek immediate medical attention if you develop any symptoms of lactic acidosis including unusual tiredness, severe drowsiness, cold skin, ...

6. glucophage
a serious-though rare-side effect of metformin is lactic acidosis. lactic acidosis occurs in one out of every 30000 patients and is fatal in 50% of cases. the symptoms of lactic acidosis are weakness, trouble breathing, ...

7. Metformin
In extreme cases this can lead to lactic acidosis, but the phenomenon is relatively rare with metformin.) The second major effect of metformin is that it is able to decrease blood glucose by improving glucose uptake in muscle cells. ...

8. DailyMed: About DailyMed
Impaired hepatic function. Since impaired hepatic function has been associated with some cases of lactic acidosis, metformin should generally be avoided in patients with clinical or laboratory evidence of hepatic disease. ...

9. metformin
some people have developed a life-threatening condition called lactic acidosis while taking metformin. get emergency medical help if you have any of these symptoms of lactic acidosis: weakness, increasing sleepiness, slow heart rate, ...

10. DB’s Medical Rants » Lactic acidosis is rarely secondary to oral meds
During current use of oral antidiabetes drugs by 50048 type 2 diabetic subjects, there were 6 identified cases of lactic acidosis. Crude incidence rate was 3.3 cases per 100000 person-years in metformin users and 4.8 cases per 100000 ...